Characterisation of DNA polymerase δ exonuclease domain mutations associated with cancer predisposition using fission yeast

Characterisation of DNA polymerase δ exonuclease domain mutations associated with cancer predisposition using fission yeast

<p>Heterozygous germline exonuclease/proofreading domain mutations (EDMs) in DNA polymerase delta (Pol δ) are linked predominantly to colorectal and endometrial cancers with microsatellite stability (MSS), such as POLD1 S478N. Pol δ synthesises the lagging strand during DNA replication and par...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखक:	Toumazou, SI
अन्य लेखक:	Kearsey, S
स्वरूप:	थीसिस
भाषा:	English
प्रकाशित:	2021
विषय:	Genetics Schizosaccharomyces pombe Cancer

समान संसाधन

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Measurements and models of synchronous growth of fission yeast induced by temperature oscillations /
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Studies on Regulation of the Cell Cycle in Fission Yeast
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प्रकाशित: (2023-09-01)

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Fission Yeast Autophagy Machinery
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प्रकाशित: (2025-01-01)

Quick-Freeze, Deep-Etch Electron Microscopy Reveals the Characteristic Architecture of the Fission Yeast Spore
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Activities and genetic interactions of fission yeast Aps1, a Nudix-type inositol pyrophosphatase and inorganic polyphosphatase
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The Effect of ATP Sulphurylase on the Prooxidant Properties of Selenate in Yeast Schizosaccharomyces pombe
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Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe
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Schizosaccharomyces pombe as a predictor toxicity tool
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Characterisation of Schizosaccharomyces pombe α-actinin
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प्रकाशित: (2016-03-01)

Characterisation of unessential genes required for survival under conditions of DNA stress
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A Normalization Protocol Reduces Edge Effect in High-Throughput Analyses of Hydroxyurea Hypersensitivity in Fission Yeast
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प्रकाशित: (2023-10-01)

Quality and Composition of Red Wine Fermented with Schizosaccharomyces pombe as Sole Fermentative Yeast, and in Mixed and Sequential Fermentations with Saccharomyces cerevisiae
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प्रकाशित: (2014-01-01)

The absence of the ribosomal protein Rpl2702 elicits the MAPK-mTOR signaling to modulate mitochondrial morphology and functions
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प्रकाशित: (2024-07-01)

Gut mycobiome alterations in obesity in geographically different regions
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प्रकाशित: (2024-12-01)

Effects of <i>rpl1001</i> Gene Deletion on Cell Division of Fission Yeast and Its Molecular Mechanism
द्वारा: Wen Yu, और अन्य
प्रकाशित: (2024-03-01)

Advanced Protocol for Molecular Characterization of Viral Genome in Fission Yeast (<i>Schizosaccharomyces pombe</i>)
द्वारा: Jiantao Zhang, और अन्य
प्रकाशित: (2024-07-01)

Combining single-molecule and expansion microscopy in fission yeast to visualize protein structures at the nanostructural level
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The Fission Yeast RNA-Binding Protein Meu5 Is Involved in Outer Forespore Membrane Breakdown during Spore Formation
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प्रकाशित: (2020-11-01)

Differences in the Volatile Profile of Apple Cider Fermented with <i>Schizosaccharomyces pombe</i> and <i>Schizosaccharomyces japonicus</i>
द्वारा: Nicola Ferremi Leali, और अन्य
प्रकाशित: (2024-02-01)

DPred_3S: identifying dihydrouridine (D) modification on three species epitranscriptome based on multiple sequence-derived features
द्वारा: Jinjin Ren, और अन्य
प्रकाशित: (2023-12-01)

FUNCTIONAL CHARACTERIZATION OF SPERMINE FAMILY TRANSPORTER caf5+ IN Schizosaccharomyces pombe (Lindner)
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प्रकाशित: (2019-10-01)

Activation of Cdc42 GTPase upon CRY2-Induced Cortical Recruitment Is Antagonized by GAPs in Fission Yeast
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प्रकाशित: (2020-09-01)

Improving Drug Sensitivity of HIV-1 Protease Inhibitors by Restriction of Cellular Efflux System in a Fission Yeast Model
द्वारा: Jiantao Zhang, और अन्य
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DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer.
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प्रकाशित: (2013)

Optimisation of quality features of new wheat beers fermented through sequential inoculation of non-Saccharomyces and Saccharomyces yeasts
द्वारा: Francesco Grieco, और अन्य
प्रकाशित: (2024-09-01)

Characterization of Shy1, the Schizosaccharomyces pombe homolog of human SURF1
द्वारा: Ying Luo, और अन्य
प्रकाशित: (2024-09-01)

Identification and characterization of a novel antifungal compound tubeimoside I targeting cell wall
द्वारा: Qiannan Liu, और अन्य
प्रकाशित: (2024-06-01)

Enhancing wine fermentation through concurrent utilization of Lachancea thermotolerans and lactic acid bacteria (Oenococcus oeni and Lactiplantibacillus plantarum) or Schizosaccharomyces pombe
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Single-Agent and Fixed-Dose Combination HIV-1 Protease Inhibitor Drugs in Fission Yeast (<i>Schizosaccharomyces pombe</i>)
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प्रकाशित: (2021-06-01)

Effects of Schizosaccharomyces pombe and Saccharomyces cerevisiae co-fermentation on the quality and flavor of pomelo wine
द्वारा: LI Anning, HUANG Zhangjun, XIANG Ling, BAI Jinrong, WU Qixiao, YU Songbai, HUANG Yina
प्रकाशित: (2024-03-01)

Pom1 gradient buffering through intermolecular auto‐phosphorylation
द्वारा: Micha Hersch, और अन्य
प्रकाशित: (2015-07-01)