Characterisation of DNA polymerase δ exonuclease domain mutations associated with cancer predisposition using fission yeast

Characterisation of DNA polymerase δ exonuclease domain mutations associated with cancer predisposition using fission yeast

<p>Heterozygous germline exonuclease/proofreading domain mutations (EDMs) in DNA polymerase delta (Pol δ) are linked predominantly to colorectal and endometrial cancers with microsatellite stability (MSS), such as POLD1 S478N. Pol δ synthesises the lagging strand during DNA replication and par...

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Bibliografiska uppgifter
Huvudupphovsman:	Toumazou, SI
Övriga upphovsmän:	Kearsey, S
Materialtyp:	Lärdomsprov
Språk:	English
Publicerad:	2021
Ämnen:	Genetics Schizosaccharomyces pombe Cancer

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av: Anwar Nasim, et al.
Publicerad: (1989)

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av: Shengnan Zheng, et al.
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av: Miroslava Pozgajova, et al.
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av: Dzivenu, O, et al.
Publicerad: (1999)

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av: Maiorano, D, et al.
Publicerad: (1995)

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av: Dan-Dan Xu, et al.
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av: Aleksei Innokentev, et al.
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av: Stevenson, A, et al.
Publicerad: (2005)

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av: Ana M. Sanchez, et al.
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av: Zsigmond Benko, et al.
Publicerad: (2011-07-01)

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av: Shreya Ghosh, et al.
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av: Štefan Fujs, et al.
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av: Consuelo Álvarez-Herrera, et al.
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av: Barbara Addario, et al.
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av: Hassan Ahmed Ezzat, et al.
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av: Ling Liu, et al.
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av: Jiantao Zhang, et al.
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av: Micha Hersch, et al.
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