Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

The key role of interleukin (IL)-23 in the pathogenesis of autoimmune and chronic inflammatory disorders is supported by the identification of IL-23 receptor (IL-23R) susceptibility alleles associated with inflammatory bowel disease, psoriasis and ankylosing spondylitis. IL-23-driven inflammation ha...

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Bibliographic Details
Main Authors: Buonocore, S, Ahern, P, Uhlig, H, Ivanov, I, Littman, DR, Maloy, K, Powrie, F
Format: Journal article
Language:English
Published: 2010