MHC-peptide tetramers for the analysis of antigen-specific T cells.

The development of the fluorescently labeled tetrameric MHC-peptide complex has enabled the direct visualization, quantification and phenotypic characterization of antigen-specific T cells using flow cytometry and has transformed our understanding of cellular immune responses. The combination of thi...

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Detalles Bibliográficos
Autores principales: Sims, S, Willberg, C, Klenerman, P
Formato: Journal article
Lenguaje:English
Publicado: 2010