Isolation, characterization, and genetic analysis of monosomic, aneuploid mutants of Candida albicans.
A white, prototrophic Candida albicans strain, heterozygous for the ADE2 gene (ade2/ADE2), was treated with the antimitotic agent methyl benzimidazole carbamate, and yielded red, adenine-requiring colonies at a rate of 4 x 10(-3), an order of magnitude higher than the spontaneous rate of Ade- colony...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
1992
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