Long-term humoral and cellular immune responses elicited by a heterologous Plasmodium vivax apical membrane antigen 1 protein prime/adenovirus boost immunization protocol.

Apical membrane antigen 1 (AMA-1) is an invasion-related Plasmodium antigen that is expressed during both intracellular and extracellular asexual stages of the parasite's life cycle, making it an ideal target for induction of humoral and cellular immune responses that can protect against malari...

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Main Authors: Bouillet, L, Dias, M, Dorigo, N, Moura, A, Russell, B, Nosten, F, Renia, L, Braga, E, Gazzinelli, RT, Rodrigues, M, Soares, I, Bruna-Romero, O
Format: Journal article
Jezik:English
Izdano: 2011