Mendelian randomization of blood lipids for coronary heart disease.

AIMS: To investigate the causal role of high-density lipoprotein cholesterol (HDL-C) and triglycerides in coronary heart disease (CHD) using multiple instrumental variables for Mendelian randomization. METHODS AND RESULTS: We developed weighted allele scores based on single nucleotide polymorphisms...

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Bibliographic Details
Main Authors: Holmes, M, Asselbergs, F, Palmer, T, Drenos, F, Lanktree, M, Nelson, C, Dale, C, Padmanabhan, S, Finan, C, Swerdlow, D, Tragante, V, van Iperen, E, Sivapalaratnam, S, Shah, S, Elbers, C, Shah, T, Engmann, J, Giambartolomei, C, White, J, Zabaneh, D, Sofat, R, McLachlan, S, Doevendans, P, Balmforth, A, Hall, A
Format: Journal article
Language:English
Published: 2014