Quality of isolated pig islets is improved using perfluorohexyloctane for pancreas storage in a split lobe model.

Quality of isolated pig islets is improved using perfluorohexyloctane for pancreas storage in a split lobe model.

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Pancreas transportation between donor center and islet production facility is frequently associated with prolonged ischemia impairing islet isolation and transplantation outcomes. It is foreseeable that shipment of pig pancreases from distant centralized biosecure breeding facilities to institutes t...

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Xehetasun bibliografikoak
Egile Nagusiak:	Brandhorst, H, Iken, M, Scott, W, Papas, K, Theisinger, B, Johnson, P, Korsgren, O, Brandhorst, D
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2013

Antzeko izenburuak

Quality of Isolated Pig Islets is Improved Using Perfluorohexyloctane for Pancreas Storage in a Split Lobe Model
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Pancreas storage in oxygenated perfluorodecalin does not restore post-transplant function of isolated pig islets pre-damaged by warm ischemia.
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Successful pancreas preservation by a perfluorocarbon-based one-layer method for subsequent pig islet isolation.
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Adaption of neutral protease activity for islet isolation from the long-term two-layer method-stored pig pancreas.
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Influence of collagenase loading on long-term preservation of pig pancreas by the two-layer method for subsequent islet isolation.
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Using HTK for prolonged pancreas preservation prior to human islet isolation.
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Pancreatic L-Glutamine Administration Protects Pig Islets from Cold Ischemic Injury and Increases Resistance toward Inflammatory Mediators
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Comparison of neutral proteases and collagenase class I as essential enzymes for human islet isolation
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Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation
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The ratio between collagenase class I and class II influences the efficient islet release from the rat pancreas.
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Pretransplant induction of HSP-70 in isolated adult pig islets decreases early islet xenograft survival.
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Enzyme development for human islet isolation: Five decades of progress or stagnation?
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Expression of complement regulatory proteins on islets of Langerhans: a comparison between human islets and islets isolated from normal and hDAF transgenic pigs.
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Induction and amelioration of environmental stress in isolated islets until transplantation
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Human islet separation utilizing a closed automated purification system.
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New class of oxygen carriers improves islet isolation from long-term stored rat pancreata.
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Isolation and Culture of the Islets of Langerhans from Mouse Pancreas
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Degraded collagenase deteriorates islet viability.
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Strategies to improve the oxygen supply to microencapsulated islets
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Prevention of early islet graft failure by selective inducible nitric oxide synthase inhibitors after pig to nude rat intraportal islet transplantation.
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The ischaemic preconditioning paradox and its implications for islet isolation from heart-beating and non heart-beating donors
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No beneficial effect of two-layer storage compared with UW-storage on human islet isolation and transplantation.
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The importance of tryptic-like activity in purified enzyme blends for efficient islet isolation.
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High seeding density induces local hypoxia and triggers a proinflammatory response in isolated human islets
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Heat-exposed pig islets are protected from inflammatory mediators but express proapoptotic proteins.
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Influence of neutral protease activity on human islet isolation outcome.
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Basement membrane proteins improve human islet survival in hypoxia: Implications for islet inflammation
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Anti-caspase-3 preconditioning increases proinsulin secretion and deteriorates posttransplant function of isolated human islets.
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Anti-caspase-3 preconditioning increases proinsulin secretion and deteriorates posttransplant function of isolated human islets
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High-dosed nicotinamide decreases early graft failure after pig to nude rat intraportal islet transplantation.
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