Direct measurement of CD4+ and CD8+ T-cell responses to CMV in HIV-1-infected subjects.

Data from murine models of chronic viral infection suggest that CD4+ T-cell responses to viral pathogens are important in sustaining the number and/or function of CD8+ cytotoxic T-cell (CTL) effectors. In this study, we used cytokine flow cytometry (CFC), staining with HLA-A*0201-peptide tetramers,...

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Bibliographic Details
Main Authors: Komanduri, K, Donahoe, S, Moretto, W, Schmidt, D, Gillespie, G, Ogg, G, Roederer, M, Nixon, D, McCune, J
Format: Journal article
Language:English
Published: 2001