Microvascular dysfunction after transient high glucose is caused by superoxide-dependent reduction in the bioavailability of NO and BH(4).

We hypothesized that transient high-glucose concentration interferes with mediation by nitric oxide (NO) of flow-induced dilation (FID) of arterioles due to enhanced production of superoxide. In isolated, pressurized (80 mmHg) rat gracilis muscle arterioles ( approximately 130 microm) after transien...

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Détails bibliographiques
Auteurs principaux: Bagi, Z, Toth, E, Koller, A, Kaley, G
Format: Journal article
Langue:English
Publié: 2004