Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosis.
The double Holliday junction (dHJ) is generally regarded to be a key intermediate of meiotic recombination, whose resolution is critical for the formation of crossover recombinants. In fission yeast, the Mus81-Eme1 endonuclease has been implicated in resolving dHJs. Consistent with this role, we sho...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2003
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