Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.

Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.

We combined two tuberculosis genome-wide association studies from Ghana and The Gambia with subsequent replication in a combined 11,425 individuals. rs4331426, located in a gene-poor region on chromosome 18q11.2, was associated with disease (combined P = 6.8 x 10(-9), odds ratio = 1.19, 95% CI = 1.1...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Thye, T, Vannberg, F, Wong, S, Owusu-Dabo, E, Osei, I, Gyapong, J, Sirugo, G, Sisay-Joof, F, Enimil, A, Chinbuah, M, Floyd, S, Warndorff, D, Sichali, L, Malema, S, Crampin, A, Ngwira, B, Teo, Y, Small, K, Rockett, K, Kwiatkowski, D, Fine, P, Hill, P, Newport, M, Lienhardt, C, Adegbola, R
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2010

Ижил төстэй зүйлс

Large-scale candidate gene study of tuberculosis susceptibility in the Karonga district of northern Malawi.
-н: Fitness, J, зэрэг
Хэвлэсэн: (2004)

Large-scale candidate gene study of leprosy susceptibility in the Karonga district of northern Malawi.
-н: Fitness, J, зэрэг
Хэвлэсэн: (2004)

CD209 genetic polymorphism and tuberculosis disease.
-н: Vannberg, F, зэрэг
Хэвлэсэн: (2008)

A hallmark of balancing selection is present at the promoter region of interleukin 10.
-н: Wilson, J, зэрэг
Хэвлэсэн: (2006)

Analysis of IL10 haplotypic associations with severe malaria.
-н: Wilson, J, зэрэг
Хэвлэсэн: (2005)

Variant G57E of mannose binding lectin associated with protection against tuberculosis caused by Mycobacterium africanum but not by M. tuberculosis.
-н: Thorsten Thye, зэрэг
Хэвлэсэн: (2011-01-01)

Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains.
-н: Christopher D Intemann, зэрэг
Хэвлэсэн: (2009-09-01)

CD209 genetic polymorphism and tuberculosis disease.
-н: Fredrik O Vannberg, зэрэг
Хэвлэсэн: (2008-01-01)

Investigation of malaria susceptibility determinants in the IFNG/IL26/IL22 genomic region.
-н: Koch, O, зэрэг
Хэвлэсэн: (2005)

IL10 haplotype associated with tuberculin skin test response but not with pulmonary TB.
-н: Thorsten Thye, зэрэг
Хэвлэсэн: (2009-01-01)

CTLA4 autoimmunity-associated genotype contributes to severe pulmonary tuberculosis in an African population.
-н: Thorsten Thye, зэрэг
Хэвлэсэн: (2009-01-01)

Linkage analysis of susceptibility to leprosy type using an IBD regression method.
-н: Wallace, C, зэрэг
Хэвлэсэн: (2004)

Genetic variants of MARCO are associated with susceptibility to pulmonary tuberculosis in a Gambian population.
-н: Bowdish, D, зэрэг
Хэвлэсэн: (2013)

Mycobacterium tuberculosis Drug Resistance, Ghana
-н: Ellis Owusu-Dabo, зэрэг
Хэвлэсэн: (2006-07-01)

Nucleotide and haplotypic diversity of the NOS2A promoter region and its relationship to cerebral malaria (vol 112, pg 379, 2003)
-н: Burgner, D, зэрэг
Хэвлэсэн: (2004)

Common variants at 11p13 are associated with susceptibility to tuberculosis.
-н: Thye, T, зэрэг
Хэвлэсэн: (2012)

Common variants at 11p13 are associated with susceptibility to tuberculosis
-н: Thye, T, зэрэг
Хэвлэсэн: (2012)

Erratum: Nucleotide and haplotypic diversity of the NOS2A promoter region and its relationship to cerebral malaria (Human Genetics (2003) vol. 112 (379-386))
-н: Burgner, D, зэрэг
Хэвлэсэн: (2004)

Cotrimoxazole prophylaxis reduces mortality in human immunodeficiency virus-positive tuberculosis patients in Karonga District, Malawi
-н: Mwaungulu Frank B.D., зэрэг
Хэвлэсэн: (2004-01-01)

A comparison of case-control and family-based association methods: the example of sickle-cell and malaria.
-н: Ackerman, H, зэрэг
Хэвлэсэн: (2005)

Allelic heterogeneity of G6PD deficiency in West Africa and severe malaria susceptibility
-н: Clark, T, зэрэг
Хэвлэсэн: (2009)

Allelic heterogeneity of G6PD deficiency in West Africa and severe malaria susceptibility.
-н: Clark, T, зэрэг
Хэвлэсэн: (2009)

Presentación 112
-н: Revista Controversia
Хэвлэсэн: (2024-11-01)

Community perceptions and practices of treatment seeking for childhood pneumonia: a mixed methods study in a rural district, Ghana
-н: Mercy Abbey, зэрэг
Хэвлэсэн: (2016-08-01)

Treatment choices for fevers in children under-five years in a rural Ghanaian district
-н: Gyapong Margaret, зэрэг
Хэвлэсэн: (2010-06-01)

CISH and susceptibility to infectious diseases.
-н: Khor, C, зэрэг
Хэвлэсэн: (2010)

Haptoglobin genotype, anaemia and malaria in Gambian children.
-н: Cox, SE, зэрэг
Хэвлэсэн: (2008)

A genetic association study in the Gambia using tagging polymorphisms in the major histocompatibility complex class III region implicates a HLA-B associated transcript 2 polymorphism in severe malaria susceptibility.
-н: Diakite, M, зэрэг
Хэвлэсэн: (2009)

Contribution of remote M.tuberculosis infection to tuberculosis disease: A 30-year population study.
-н: Judith R Glynn, зэрэг
Хэвлэсэн: (2023-01-01)

KUA 112-3 & KUP 112-3 & KUI 112-3 - KIMIA AM II OKT. 1987-88
-н: PPSK, Pusat Pengajian Sains Kimia
Хэвлэсэн: (1988)

BOI112/BOM112 - Ekologi Asas – September - Oktober 2000
-н: PPSKJ, Pusat Pengajian Sains Kajihayat
Хэвлэсэн: (2000)

KUA 112 & KUI 112 - KIMIA AM II JUN 1989
-н: PPSK, Pusat Pengajian Sains Kimia
Хэвлэсэн: (1989)

KUA112-KUI112 - KIMIA AM II JUN 1992
-н: PPSK, Pusat Pengajian Sains Kimia
Хэвлэсэн: (1992)

KUA 112 - KUI 112 - KIMIA AM II JUN 1993.
-н: PPSK, Pusat Pengajian Sains Kimia
Хэвлэсэн: (1993)

Implications of inter-population linkage disequilibrium patterns on the approach to a disease association study in the human MHC class III.
-н: Hanchard, N, зэрэг
Хэвлэсэн: (2006)

Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children.
-н: Atkinson, S, зэрэг
Хэвлэсэн: (2008)

Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotype
-н: Atkinson, S, зэрэг
Хэвлэсэн: (2006)

Salmos 111-112
-н: Waldecir Gonzaga, зэрэг
Хэвлэсэн: (2022-09-01)

Persae, 111-112
-н: Esteban Calderón Dorda
Хэвлэсэн: (1983-06-01)

KUA 112 & KUI 112 - KIMIA AM II OKT-NOV. 1989
-н: PPSK, Pusat Pengajian Sains Kimia
Хэвлэсэн: (1989)