Alpha-synuclein in Parkinson's disease: molecular pathogenesis and development of genome engineering-based silencing approaches
<p>The ability to reprogram adult somatic cells into induced pluripotent stem cells (iPSCs) and subsequent development of protocols for their differentiation into disease-relevant cell types have enabled in-depth molecular analyses of multiple disease states as hitherto impossible. Parkinson’s...
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Format: | Thesis |
Language: | English |
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2015
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