Vascular pathology in multiple sclerosis: reframing pathogenesis around the blood-brain barrier

Blood-brain barrier (BBB) disruption has long been recognised as an important early feature of multiple sclerosis (MS) pathology. Traditionally, this has been seen as a by-product of the myelin-specific immune response. Here, we consider whether vascular changes instead play a central role in diseas...

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Bibliographic Details
Main Authors: Spencer, J, Bell, J, DeLuca, G
Format: Journal article
Published: BMJ Publishing Group 2017