Antigen-specific T cell unresponsiveness in cloned helper T cells mediated via the CD2 or CD3/Ti receptor pathways.

We have investigated the role of the CD2 protein in the negative regulation of immune function and report that similar to antigen and anti-CD3, the monoclonal anti-CD2 antibodies (T112 and T113) can induce specific unresponsiveness. Antigen and anti-CD2 tolerogenic signals both down-regulated the ph...

詳細記述

書誌詳細
主要な著者: Lamb, JR, Zanders, E, Sewell, W, Crumpton, M, Feldmann, M, Owen, M
フォーマット: Journal article
言語:English
出版事項: 1987