Relationship between chromatin structure and sensitivity to molecularly targeted auger electron radiation therapy

Purpose: The open structure of euchromatin renders it susceptible to DNA damage by ionizing radiation (IR) compared with compact heterochromatin. The effect of chromatin configuration on the efficacy of Auger electron radiotherapy was investigated. Methods and Materials: Chromatin structure was alte...

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Autori principali: Terry, S, Vallis, K
Natura: Journal article
Lingua:English
Pubblicazione: 2012