Relationship between chromatin structure and sensitivity to molecularly targeted auger electron radiation therapy
Purpose: The open structure of euchromatin renders it susceptible to DNA damage by ionizing radiation (IR) compared with compact heterochromatin. The effect of chromatin configuration on the efficacy of Auger electron radiotherapy was investigated. Methods and Materials: Chromatin structure was alte...
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
2012
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