α7-Acetylcholine receptor antibodies in two patients with Rasmussen encephalitis

Rasmussen encephalitis (RE) sera were screened for antibodies to human α7 nicotinic acetylcholine receptors (nAChRs) using electrophysiology, calcium imaging, and ligand binding assays. Sera from two of nine patients with RE blocked ACh-induced currents through α7 nAChRs and the ACh-induced rise in...

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Bibliographic Details
Main Authors: Watson, R, Jepson, J, Bermudez, I, Alexander, S, Hart, Y, McKnight, K, Roubertie, A, Fecto, F, Valmier, J, Sattelle, D, Beeson, D, Vincent, A, Lang, B
Format: Journal article
Language:English
Published: 2005