GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development.
Thymocyte-expressed molecule involved in selection (THEMIS) is a recently identified regulator of thymocyte positive selection. THEMIS's mechanism of action is unknown, and whether it has a role in TCR-proximal signaling is controversial. In this article, we show that THEMIS and the adapter mol...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2013
|