Tethered fluorophore motion: studying large DNA conformational changes by single-fluorophore imaging.

We have previously introduced tethered fluorophore motion (TFM), a single-molecule fluorescence technique that monitors the effective length of a biopolymer such as DNA. TFM uses the same principles as tethered particle motion (TPM) but employs a single fluorophore in place of the bead, allowing TFM...

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Detalhes bibliográficos
Principais autores: May, P, Pinkney, J, Zawadzki, P, Evans, G, Sherratt, D, Kapanidis, A
Formato: Journal article
Idioma:English
Publicado em: Elsevier 2014
Assuntos: