Development of novel nuclease inhibitors as potential anticancer agents
<p>SNM1A and SNM1B are 5' to 3' exonucleases that are involved in the repair of DNA interstrand crosslinks (ICLs); the endonuclease SNM1C is involved in the repair of DNA double strand breaks via non-homologous end-joining. Cells depleted in SNM1A and SNM1B show increased sensitivity...
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| Format: | Thesis |
| Language: | English |
| Published: |
2022
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