Association analysis of the vitamin D receptor gene, the type I collagen gene COL1A1, and the estrogen receptor gene in idiopathic osteoarthritis.

OBJECTIVE: Evidence has accumulated supporting a role for genes in the etiology of osteoarthritis (OA). Several candidates have been targeted as potential susceptibility loci including genes that are involved in the regulation of bone density. Genetic association analysis has suggested a role for th...

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Autori principali: Loughlin, J, Sinsheimer, J, Mustafa, Z, Carr, A, Clipsham, K, Bloomfield, V, Chitnavis, J, Bailey, A, Sykes, B, Chapman, K
Natura: Journal article
Lingua:English
Pubblicazione: 2000