UBR5 interacts with the replication fork and protects DNA replication from DNA polymerase η toxicity

Accurate DNA replication is critical for the maintenance of genome integrity and cellular survival. Cancer-associated alterations often involve key players of DNA replication and of the DNA damage-signalling cascade. Post-translational modifications play a fundamental role in coordinating replicatio...

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Bibliografiska uppgifter
Huvudupphovsmän: Cipolla, L, Bertoletti, F, Maffia, A, Liang, C, Lehmann, A, Cohn, M, Sabbioneda, S
Materialtyp: Journal article
Språk:English
Publicerad: Oxford University Press 2019