ELOVL5 is a critical and targetable fatty acid elongase in prostate cancer

The androgen receptor (AR) is the key oncogenic driver of prostate cancer, and despite implementation of novel AR targeting therapies, outcomes for metastatic disease remain dismal. There is an urgent need to better understand androgen-regulated cellular processes to more effectively target the AR-d...

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Bibliographic Details
Main Authors: Centenera, MM, Scott, JS, Machiels, J, Nassar, ZD, Miller, DC, Zininos, I, Dehairs, J, Burvenich, IJG, Zadra, G, Chetta, P, Bango, C, Evergren, E, Ryan, NK, Gillis, JL, Mah, CY, Tieu, T, Hanson, AR, Carelli, R, Bloch, K, Panagopoulos, V, Waelkens, E, Derua, R, Williams, ED, Evdokioou, A, Cifuentes-Rius, A, Voelcker, NH, Mills, IG, Tilley, WD, Scott, AM, Loda, M, Selth, LA, Swinnen, JV, Butler, LM
Format: Journal article
Language:English
Published: American Association for Cancer Research 2021