Influenza virion-derived viral ribonucleoproteins synthesize both mRNA and cRNA in vitro.

The mechanisms regulating the synthesis of mRNA, cRNA, and viral genomic RNA (vRNA) by the influenza A virus RNA-dependent RNA polymerase are not fully understood. Early results suggested that the RNA polymerase "switched" from a transcriptase to a replicase during the viral life cycle in...

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Bibliographic Details
Main Authors: Vreede, F, Brownlee, G
Format: Journal article
Language:English
Published: 2007