Influenza virion-derived viral ribonucleoproteins synthesize both mRNA and cRNA in vitro.
The mechanisms regulating the synthesis of mRNA, cRNA, and viral genomic RNA (vRNA) by the influenza A virus RNA-dependent RNA polymerase are not fully understood. Early results suggested that the RNA polymerase "switched" from a transcriptase to a replicase during the viral life cycle in...
Main Authors: | Vreede, F, Brownlee, G |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2007
|
Similar Items
-
Different de novo initiation strategies are used by influenza virus RNA polymerase on its cRNA and viral RNA promoters during viral RNA replication.
by: Deng, T, et al.
Published: (2006) -
In vitro transcription and polymerase binding studies of the termini of influenza A virus cRNA: evidence for a cRNA panhandle.
by: Pritlove, D, et al.
Published: (1995) -
Polyadenylation of influenza virus mRNA transcribed in vitro from model virion RNA templates: requirement for 5' conserved sequences.
by: Pritlove, D, et al.
Published: (1998) -
Direct evidence that the poly(A) tail of influenza A virus mRNA is synthesized by reiterative copying of a U track in the virion RNA template.
by: Poon, L, et al.
Published: (1999) -
Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding.
by: Maier, H, et al.
Published: (2008)