Analysis of the tunicamycin biosynthetic gene cluster of Streptomyces chartreusis reveals new insights into tunicamycin production and immunity

The tunicamycin biosynthetic gene cluster of Streptomyces chartreusis consists of 14 genes (tunA-N) with a high degree of apparent translational coupling. Transcriptional analysis revealed that all of these genes are likely to be transcribed as a single operon from two promoters, tunp1 and tunp2. In...

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Autori principali: Widdick, D, Royer, S, Wang, H, Vior, N, Gomez-Escribano, J, Davis, B, Bibb, M
Natura: Journal article
Lingua:English
Pubblicazione: American Society for Microbiology 2018