Use of synthetic vectors for neutralising antibody resistant delivery of replicating adenovirus DNA.

Use of synthetic vectors to deliver genomes of conditionally replicating lytic viruses combines the strengths of viral and non-viral approaches by enabling neutralising antibody resistant deployment of cancer virotherapy. Adenovirus is particularly suitable for this application since all proteins es...

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Bibliographic Details
Main Authors: Carlisle, R, Briggs, S, Hale, AB, Green, N, Fisher, K, Etrych, T, Ulbrich, K, Mautner, V, Seymour, L
Format: Journal article
Language:English
Published: 2006