Culture adaptation of malaria parasites selects for convergent loss-of-function mutants
Cultured human pathogens may differ significantly from source populations. To investigate the genetic basis of laboratory adaptation in malaria parasites, clinical Plasmodium falciparum isolates were sampled from patients and cultured in vitro for up to three months. Genome sequence analysis was per...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Published: |
Nature Publishing Group
2017
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