Cognate MHC-TCR interaction leads to apoptosis of antigen-presenting cells.

Antigen presentation to T lymphocytes has been characterized extensively in terms of T lymphocyte activation and eventual cell death. In contrast, little is known about the consequences of antigen presentation for the antigen-presenting cell (APC). We have determined the outcome of major histocompat...

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Bibliographic Details
Main Authors: Setterblad, N, Blancheteau, V, Delaguillaumie, A, Michel, F, Bécart, S, Lombardi, G, Acuto, O, Charron, D, Mooney, N
Format: Journal article
Language:English
Published: 2004