Population analysis of antiviral T cell responses using MHC class I-peptide tetramers.

MHC class I-peptide tetrameric complexes ('tetramers') have revolutionized the study of antiviral CD8+ T cell responses. They allow accurate quantification of immune responses ex vivo independent of function, with high levels of sensitivity. They have revealed unexpectedly large frequencie...

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Bibliographic Details
Main Authors: Komatsu, H, Sierro, S, V Cuero, A, Klenerman, P
Format: Journal article
Language:English
Published: 2003