Population analysis of antiviral T cell responses using MHC class I-peptide tetramers.

MHC class I-peptide tetrameric complexes ('tetramers') have revolutionized the study of antiviral CD8+ T cell responses. They allow accurate quantification of immune responses ex vivo independent of function, with high levels of sensitivity. They have revealed unexpectedly large frequencie...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Komatsu, H, Sierro, S, V Cuero, A, Klenerman, P
Format: Journal article
Sprache:English
Veröffentlicht: 2003