Population analysis of antiviral T cell responses using MHC class I-peptide tetramers.
MHC class I-peptide tetrameric complexes ('tetramers') have revolutionized the study of antiviral CD8+ T cell responses. They allow accurate quantification of immune responses ex vivo independent of function, with high levels of sensitivity. They have revealed unexpectedly large frequencie...
Main Authors: | Komatsu, H, Sierro, S, V Cuero, A, Klenerman, P |
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Format: | Journal article |
Language: | English |
Published: |
2003
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