Population analysis of antiviral T cell responses using MHC class I-peptide tetramers.

MHC class I-peptide tetrameric complexes ('tetramers') have revolutionized the study of antiviral CD8+ T cell responses. They allow accurate quantification of immune responses ex vivo independent of function, with high levels of sensitivity. They have revealed unexpectedly large frequencie...

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Detalles Bibliográficos
Main Authors: Komatsu, H, Sierro, S, V Cuero, A, Klenerman, P
Formato: Journal article
Idioma:English
Publicado: 2003