Arthropod-derived histamine-binding protein prevents murine allergic asthma.

Because histamine receptor type I blockade attenuates allergic asthma, we asked whether complete neutralization of histamine by an arthropod-derived, high affinity histamine-binding protein (EV131) would prevent allergic asthma. Intranasal administration of EV131 given before Ag challenge in immuniz...

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Bibliographic Details
Main Authors: Couillin, I, Maillet, I, Vargaftig, B, Jacobs, M, Paesen, G, Nuttall, P, Lefort, J, Moser, R, Weston-Davies, W, Ryffel, B
Format: Journal article
Language:English
Published: 2004