CpG-creating mutations are costly in many human viruses

CpG-creating mutations are costly in many human viruses

Mutations can occur throughout the virus genome and may be beneficial, neutral or deleterious. We are interested in mutations that yield a C next to a G, producing CpG sites. CpG sites are rare in eukaryotic and viral genomes. For the eukaryotes, it is thought that CpG sites are rare because they ar...

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Bibliographic Details
Main Authors: Caudill, VR, Qin, S, Winstead, R, Kaur, J, Tisthammer, K, Pineda, EG, Solis, C, Cobey, S, Bedford, T, Carja, O, Eggo, RM, Koelle, K, Lythgoe, K, Regoes, R, Roy, S, Allen, N, Aviles, M, Baker, BA, Bauer, W, Bermudez, S, Carlson, C, Castellanos, E, Catalan, FL, Chemel, AK, Elliot, J, Evans, D, Fiutek, N, Fryer, E, Goodfellow, SM, Hecht, M, Hopp, K, Hopson, ED, Jaberi, A, Kinney, C, Lao, D, Le, A, Lo, J, Lopez, AG, López, A, Lorenzo, FG, Luu, GT, Mahoney, AR, Rebecca L Melton, Nascimento, GD, Pradhananga, A, Rodrigues, NS, Shieh, A, Sims, J, Singh, R, Sulaeman, H
Format: Journal article
Language:English
Published: Springer Nature 2020

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