Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase.
Atopic dermatitis is a common pruritic skin disease in which barrier dysfunction and cutaneous inflammation play a role in pathogenesis. Mechanisms underlying the associated inflammation are not fully understood, and while CD1a-expressing Langerhans cells are known to be enriched within lesions, the...
Những tác giả chính: | , , , , , , , , , , , , , , , , , , , , , |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
American Association for the Advancement of Science
2016
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