A phase III, randomized, non-inferiority trial to assess the efficacy and safety of dihydroartemisinin-piperaquine in comparison with artesunate-mefloquine in patients with uncomplicated Plasmodium falciparum malaria in southern Laos.

We conducted an open, randomized clinical trial of oral dihydroartemisinin-piperaquine (DP) versus artesunate-mefloquine (AM) in 300 patients in Laos with uncomplicated Plasmodium falciparum malaria as part of a multicentre study in Asia. Survival analysis and adjustment for re-infection showed that...

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Detalles Bibliográficos
Autores principales: Mayxay, M, Keomany, S, Khanthavong, M, Souvannasing, P, Stepniewska, K, Khomthilath, T, Keola, S, Pongvongsa, T, Phompida, S, Ubben, D, Valecha, N, White, N, Newton, P
Formato: Journal article
Lenguaje:English
Publicado: 2010