Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site.

Positive allosteric modulators of alpha7 nicotinic acetylcholine receptors (nAChRs) have attracted considerable interest as potential tools for the treatment of neurological and psychiatric disorders such as Alzheimer's disease and schizophrenia. However, despite the potential therapeutic usefu...

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Autors principals: Young, G, Zwart, R, Walker, A, Sher, E, Millar, N
Format: Journal article
Idioma:English
Publicat: 2008