Investigating the role of alternative polyadenylation in neuronal differentiation and neurodegeneration
<p>Over 70% of human genes can undergo alternative polyadenylation (APA), whereby they utilise different polyadenylation (poly(A)) sites found in the 3’UTR (3’UTR-APA) or in the upstream coding region of the gene (upstream-APA). The 3’UTR harbours regulatory cis-elements which can mediate the...
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| Format: | Thesis |
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2017
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