Combined structural and immunological refinement of HIV-1 HLA-B8-restricted cytotoxic T lymphocyte epitopes.

This study demonstrates that use of structural information improves the definition and optimization of cytotoxic T lymphocyte (CTL) epitopes. Epitope optimization usually requires numerous truncated peptides or a reverse immunogenetic approach, where the peptide binding motif is used to predict epit...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Goulder, P, Reid, S, Price, D, O'Callaghan, C, Mcmichael, A, Phillips, R, Jones, E
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 1997