Exocytotic properties of human pancreatic beta-cells.

Pancreatic beta-cells secrete insulin in response to elevated blood glucose via Ca(2+)-dependent fusion of secretory granules with the plasma membrane (regulated exocytosis). While exocytosis has been extensively investigated in rodent beta-cells, studies on human beta-cells are scarce. We have char...

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Bibliographic Details
Main Authors: Braun, M, Ramracheya, R, Johnson, P, Rorsman, P
Format: Journal article
Language:English
Published: 2009