A method for identifying genetic heterogeneity within phenotypically defined disease subgroups
Many common diseases show wide phenotypic variation. We present a statistical method for determining whether phenotypically defined subgroups of disease cases represent different genetic architectures, in which disease-associated variants have different effect sizes in two subgroups. Our method mode...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Springer Nature
2016
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