Synthesis, affinity for complementary RNA and DNA, and enzymatic stability of Triazole-linked locked nucleic acids (t-LNAs)

Dinucleoside phosphoramidites containing a triazole internucleotide linkage flanked by locked nucleic acid (LNA) were synthesized and incorporated into oligonucleotides (ONs). ONs bearing both LNA and triazole at multiple sites were obtained and their biophysical properties including enzymatic stabi...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Kumar, P, Truong, L, Baker, Y, El-Sagheer, A, Brown, T
Formatua: Journal article
Hizkuntza:English
Argitaratua: American Chemical Society 2018