Differential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2.
The basic helix-loop-helix (bHLH) factor Hand1 plays an essential role in cardiac morphogenesis, and yet its precise function remains unknown. Protein-protein interactions involving Hand1 provide a means of determining how Hand1-induced gene expression in the developing heart might be regulated. Han...
Main Authors: | , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2004
|