Fluorescence-aided molecule sorting: analysis of structure and interactions by alternating-laser excitation of single molecules.

We use alternating-laser excitation to achieve fluorescence-aided molecule sorting (FAMS) and enable simultaneous analysis of biomolecular structure and interactions at the level of single molecules. This was performed by labeling biomolecules with fluorophores that serve as donor-acceptor pairs for...

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Bibliographic Details
Main Authors: Kapanidis, A, Lee, N, Laurence, T, Doose, S, Margeat, E, Weiss, S
Format: Journal article
Language:English
Published: 2004