Probing the limits of Q-tag bioconjugation of antibodies
Site-selective labelling of antibodies (Abs) can circumvent problems from heterogeneity of conventional conjugation. Here, we evaluate the industrially-applied chemoenzymatic ‘Q-tag’ strategy based on transglutaminase-mediated (TGase) amide-bond formation in the generation of 89Zr-radiolabelled anti...
Main Authors: | , , , , , , , , , |
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Format: | Journal article |
Published: |
Royal Society of Chemistry
2019
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