Probing the limits of Q-tag bioconjugation of antibodies

Probing the limits of Q-tag bioconjugation of antibodies

Site-selective labelling of antibodies (Abs) can circumvent problems from heterogeneity of conventional conjugation. Here, we evaluate the industrially-applied chemoenzymatic ‘Q-tag’ strategy based on transglutaminase-mediated (TGase) amide-bond formation in the generation of 89Zr-radiolabelled anti...

Full description

Bibliographic Details
Main Authors:	Marculescu, C, Lakshminarayanan, A, Gault, J, Knight, JC, Folkes, LK, Spink, T, Robinson, CV, Vallis, K, Davis, BG, Cornelissen, B
Format:	Journal article
Published:	Royal Society of Chemistry 2019

Similar Items

Scaling-down antibody radiolabeling reactions with zirconium-89
by: Knight, JC, et al.
Published: (2016)

An efficient system for bioconjugation based on a widely applicable engineered O-glycosylation tag <subtitle>Short title: Controlled bioconjugation via O-glycan engineering</subtitle>
by: Thomas V. Murray, et al.
Published: (2021-01-01)

Liquid phase separation techniques for the characterization of monoclonal antibodies and bioconjugates
by: Ettore Gilardoni, et al.
Published: (2022-11-01)

Bioconjugation of a PNA Probe to Zinc Oxide Nanowires for Label-Free Sensing
by: Teresa Crisci, et al.
Published: (2021-02-01)

Engineering a Novel Modular Adenoviral mRNA Delivery Platform Based on Tag/Catcher Bioconjugation
by: Kexin Geng, et al.
Published: (2023-11-01)

Perspectives in bioconjugate chemistry /
by: Meares, Claude F.
Published: (1993)

Palladium reagents for bioconjugation
by: Rojas, Anthony J. (Anthony Jose)
Published: (2019)

Arylation chemistry for bioconjugation
by: Zhang, Chi, et al.
Published: (2020)

Bioconjugation strategies for oligonucleotide functionalisation
by: Chik, G
Published: (2023)

Bioconjugation of triosmium carbonyl clusters
by: Tan, Yu Qian
Published: (2017)

Preparation and Investigation of Silver Nanoparticle–Antibody Bioconjugates for Electrochemical Immunoassay of Tick-Borne Encephalitis
by: Yekaterina Khristunova, et al.
Published: (2019-05-01)

Antibody and antibody fragments site-specific conjugation using new Q-tag substrate of bacterial transglutaminase
by: Meddy El Alaoui, et al.
Published: (2024-02-01)

In vivo pretargeted imaging of HER2 and TAG-72 expression using the HaloTag enzyme
by: Knight, J, et al.
Published: (2017)

Functionalized glycolipids for potential bioconjugation of vesicles
by: Tabandeh, Mojtaba, et al.
Published: (2018)

Vinyl thianthrenium-mediated cysteine bioconjugation
by: Huijuan Guo
Published: (2024-02-01)

Medicinal Applications of Metal–Peptide Bioconjugates
by: Nils Metzler-Nolte
Published: (2007-11-01)

Organometallic palladium reagents for cysteine bioconjugation
by: Vinogradova, Ekaterina V., et al.
Published: (2017)

Bioconjugation Strategies for Microtoroidal Optical Resonators
by: Heather K. Hunt, et al.
Published: (2010-10-01)

Capillary electrophoresis for the characterization of quantum dots after non-selective or selective bioconjugation with antibodies for immunoassay
by: Lai Edward PC, et al.
Published: (2008-10-01)

Impact of Bioconjugation on Structure and Function of Antibodies for Use in Immunoassay by Hydrogen-Deuterium Exchange Mass Spectrometry
by: Luise Luckau, et al.
Published: (2022-07-01)

Probing membrane protein-lipid interactions
by: Agasid, MT, et al.
Published: (2021)

Quantum dot bioconjugates for ultrasensitive nonisotopic detection /
by: 270563 Chan, Warren C. W, et al.

Pullulan Based Bioconjugates for Ocular Dexamethasone Delivery
by: Eva Kicková, et al.
Published: (2021-05-01)

Panchromatic Absorbers Tethered for Bioconjugation or Surface Attachment
by: Rui Liu, et al.
Published: (2022-10-01)

Protein Synthesis and Bioconjugation for Design of Antimicrobial Conjugates
by: Saebi, Azin
Published: (2023)

Organometallic Palladium Reagents for Polypeptide Bioconjugation and Macrocyclization
by: Mallek, Aaron J.
Published: (2022)

Palladium–peptide oxidative addition complexes for bioconjugation
by: Rojas, Anthony J, et al.
Published: (2022)

Silicon-containing thiol-specific bioconjugating reagent
by: Zhang, Zhenguo, et al.
Published: (2024)

Bioconjugated gold nanorods for cellular imaging and therapy.
by: Teo, Jye Yng.
Published: (2012)

From Ugi Multicomponent Reaction to Linkers for Bioconjugation
by: Iván Ramos-Tomillero, et al.
Published: (2020-03-01)

Combined Antibody Tagged HRP Gold Nanoparticle Probe for Effective PCV2 Screening in Pig Farms
by: Zhang S, et al.
Published: (2022-07-01)

<i>LoopTag</i> FRET Probe System for Multiplex qPCR Detection of <i>Borrelia</i> Species
by: Henning Hanschmann, et al.
Published: (2021-10-01)

Peptide-Based Bioconjugates and Therapeutics for Targeted Anticancer Therapy
by: Seong-Bin Yang, et al.
Published: (2022-06-01)

s-Triazine: A Privileged Structure for Drug Discovery and Bioconjugation
by: Anamika Sharma, et al.
Published: (2021-02-01)

Photochemical Synthesis of the Bioconjugate Folic Acid-Gold Nanoparticles
by: John Castillo, et al.
Published: (2013-09-01)

Exploiting Protein N-Terminus for Site-Specific Bioconjugation
by: Lucia De Rosa, et al.
Published: (2021-06-01)

Lipid Formulations and Bioconjugation Strategies for Indomethacin Therapeutic Advances
by: Anna Gliszczyńska, et al.
Published: (2021-03-01)

Enzymatic Bioconjugation: A Perspective from the Pharmaceutical Industry
by: Aaron Debon, et al.
Published: (2023-05-01)

Synthesis and fluorexcence studies of a xanthone-phosphatidylethanolamine bioconjugate
by: Catarina Gonçalves, et al.
Published: (2022-04-01)

Synthesis of Lasalocid-Based Bioconjugates and Evaluation of Their Anticancer Activity
by: Michał Antoszczak, et al.
Published: (2022-01-01)