Probing the limits of Q-tag bioconjugation of antibodies

Probing the limits of Q-tag bioconjugation of antibodies

Site-selective labelling of antibodies (Abs) can circumvent problems from heterogeneity of conventional conjugation. Here, we evaluate the industrially-applied chemoenzymatic ‘Q-tag’ strategy based on transglutaminase-mediated (TGase) amide-bond formation in the generation of 89Zr-radiolabelled anti...

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Bibliografische gegevens
Hoofdauteurs:	Marculescu, C, Lakshminarayanan, A, Gault, J, Knight, JC, Folkes, LK, Spink, T, Robinson, CV, Vallis, K, Davis, BG, Cornelissen, B
Formaat:	Journal article
Gepubliceerd in:	Royal Society of Chemistry 2019

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