Foxp3 drives oxidative phosphorylation and protection from lipotoxicity.

Tregs can adopt a catabolic metabolic program with increased capacity for fatty acid oxidation-fueled oxidative phosphorylation (OXPHOS). It is unclear why this form of metabolism is favored in Tregs and, more specifically, whether this program represents an adaptation to the environment and develop...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Howie, D, Cobbold, S, Adams, E, Ten Bokum, A, Necula, A, Zhang, W, Huang, H, Roberts, D, Thomas, B, Hester, S, Vaux, D, Betz, A, Waldmann, H
Μορφή: Journal article
Γλώσσα:English
Έκδοση: American Society for Clinical Investigation 2017