Foxp3 drives oxidative phosphorylation and protection from lipotoxicity.
Tregs can adopt a catabolic metabolic program with increased capacity for fatty acid oxidation-fueled oxidative phosphorylation (OXPHOS). It is unclear why this form of metabolism is favored in Tregs and, more specifically, whether this program represents an adaptation to the environment and develop...
Κύριοι συγγραφείς: | , , , , , , , , , , , , |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
American Society for Clinical Investigation
2017
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