Metabolic-activity based assessment of antimicrobial effects by D2O-labeled Single-Cell Raman Microspectroscopy
To combat the spread of antibiotic resistance, methods that quantitatively assess the metabolism-inhibiting effects of drugs in a rapid and culture-independent manner are urgently needed. Here using four oral bacteria as models, we show that heavy water (D2O)-based single-cell Raman microspectroscop...
Những tác giả chính: | , , , , , , |
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Định dạng: | Journal article |
Được phát hành: |
American Chemical Society
2017
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